Transcranial Pulse Stimulation (TPS): Advanced Ultrasound Brain Stimulation for Alzheimer’s Care

Transcranial Pulse Stimulation (TPS) is a non-invasive brain stimulation technology that uses targeted ultrasound pulses to treat Alzheimer’s disease, particularly from early to moderate stages. At PYONG Rehabilitation Penthouse, we provide this Swiss-innovated, world-class technology to help restore cognitive functions without the need for surgery or anesthesia.

What is TPS?

TPS delivers ultra-short ultrasound pulses that penetrate the skull to precisely target specific brain regions. Unlike continuous waves, TPS uses “rhythmic short pulses” to prevent heat buildup in brain tissue. This allows physicians to map the treatment path based on each patient’s individual brain imaging (MRI), ensuring unmatched precision.

Why Choose TPS at PYONG Rehabilitation Penthouse?

Located at Gaysorn Tower (11th Floor), our clinic is one of the few leading facilities in Thailand offering the latest TPS technology from Switzerland.

• Deep Stimulation (8 cm): Our TPS device reaches up to 8 cm deep into the brain—deeper than most non-invasive stimulation methods.
• BodyTrack® Technology: Real-time MRI-linked tracking ensures the pulses hit the exact target area with surgical precision.
• Physiatrist-Led Care: Every step—from assessment to protocol selection and monitoring—is supervised by Rehabilitation Physicians.
• Multidisciplinary Synergy: We integrate TPS with a holistic “Penthouse Clinic” program, including Physical Therapy, Occupational Therapy, Speech Therapy, and Clinical Psychology.
• Prime Location: Conveniently located at BTS Chit Lom, making it easy for families and caregivers to visit.

How TPS Works: The Science of Recovery

TPS utilizes Mechanotransduction—using mechanical stimulation from ultrasound pulses to influence neural networks responsible for memory and attention. It promotes microcirculation and brain plasticity.

The Treatment Journey:

1. Specialist Assessment: Clinical evaluation and memory testing (MoCA/MMSE/ADAS-Cog).
2. MRI Mapping: Planning the stimulation sites based on the patient’s individual MRI.
3. Treatment Session: Approximately 6,000 pulses per session, lasting 30–45 minutes.
4. No Downtime: Patients can return home immediately after the session.

Typical Protocol: An initial course of 6 sessions within 2 weeks, followed by “Booster” sessions every 4–6 weeks to maintain results.

Who is TPS for?

• Early to moderate Alzheimer’s patients.
• Individuals with Mild Cognitive Impairment (MCI) involving memory or attention issues.
• Those experiencing frequent forgetfulness or difficulty managing multi-step tasks.
• Patients seeking non-surgical alternatives to supplement brain health.
• Individuals who may not respond well to or cannot tolerate the side effects of certain medications.

Expected Results & Safety

• Short-term: Some patients report feeling “clearer,” improved focus, and a slight lift in mood within the first 1–2 weeks.
• Long-term: Research indicates improved cognitive scores (such as ADAS-Cog) that can be sustained with periodic booster sessions.
• Safety: Most common side effects are mild and temporary, such as slight headaches or fatigue.
• Contraindications: Not suitable for patients with metal implants in the head, brain pacemakers, blood clotting disorders, or brain tumors.

Frequently Asked Questions (FAQ)

1. How does TPS differ from TMS? TPS uses targeted ultrasound pulses, while TMS uses electromagnetic fields. Both are non-surgical, but TPS can reach deeper brain structures more precisely.
2. What should I prepare? A recent Brain MRI is required for precise mapping. Please bring your current medication list and medical history for the physician’s review.
3. Is it painful? The procedure is generally painless. Patients only feel the movement of the probe and the cooling gel on the scalp.

Experience Excellence in Brain Rehabilitation

At PYONG Rehabilitation Clinic, our goal is “Better Quality of Life for Patients and Families.”

Consult our specialists today > 📍 Gaysorn Tower, 11th Floor (BTS Chit Lom)

LINE: @pyongrehab

Tel: (+66) 02 124 3388